Research & Innovation

Advancing the Future of Eye Care

At Shri Ganapati Netralaya, research is an integral part of our commitment to advancing ophthalmic knowledge, improving patient outcomes and bringing evidence-based innovations into clinical practice.

Research at SGN

Clinical Excellence Supported by Research

Shri Ganapati Netralaya – Eye Hospital & Research Centre is committed to developing and promoting ophthalmic research that addresses important clinical problems and contributes to better eye health outcomes.

Our research activities span clinical studies, observational research, surgical outcomes, imaging, diagnostics, genetics and emerging technologies in ophthalmology.

By bringing clinicians, researchers and patients together, we aim to generate meaningful evidence that can support better diagnosis, treatment and prevention of vision-threatening diseases.

Our research philosophy: Every research initiative should ultimately contribute to safer, more effective and accessible eye care.
Our Focus

Areas Where Research Meets Patient Care

Our research programme focuses on clinically relevant questions across multiple areas of ophthalmology.

Clinical Ophthalmology

Research addressing diagnosis, management and outcomes across major ophthalmic conditions.

Surgical Outcomes

Evaluation of surgical techniques, safety, effectiveness and long-term patient outcomes.

Imaging & Diagnostics

Research involving modern ophthalmic imaging, diagnostics and objective assessment of disease.

Genetics & Inherited Eye Disease

Investigation of inherited retinal and ocular disorders with a focus on genetic understanding.

Technology & Innovation

Exploring technologies that can improve diagnosis, treatment planning, monitoring and patient care.

Evidence & Outcomes

Generating clinical evidence through systematic collection, analysis and interpretation of patient outcomes.

Research Highlights

Building Evidence Through Clinical Research

Our research ecosystem brings together clinical expertise, structured data collection and responsible scientific investigation.

Clinical Studies

Studies designed around clinically meaningful ophthalmic questions.

Observational Research

Structured observation of disease patterns, treatments and outcomes.

Ethical Oversight

Research conducted with appropriate ethical and participant safeguards.

Collaboration

Opportunities for collaboration with clinicians and research institutions.

Research Capabilities

From Clinical Question to Evidence

Research at SGN is supported by a multidisciplinary approach that connects clinical care with scientific investigation.

  • Clinical study planning and protocol development
  • Patient recruitment and informed consent
  • Structured clinical data collection
  • Ophthalmic imaging and diagnostic assessment
  • Surgical and treatment outcome assessment
  • Follow-up and longitudinal monitoring
  • Data analysis and scientific reporting

Responsible Research

Patient safety, privacy and ethical research practices remain central to every research activity.

Participant Safety
Appropriate safeguards throughout research participation.
Informed Consent
Participants receive relevant information before participation.
Confidentiality
Research information is handled with appropriate confidentiality safeguards.
Ethical Oversight
Research proposals undergo appropriate ethical review.
Clinical Research

Current Research Studies

Selected research studies and projects associated with Shri Ganapati Netralaya.

Clinical Trial

A Phase 1/2a Multi-Center, Dose-Escalation, Dose-Expansion Study to Evaluate the Safety and Efficacy of Eyecyte-RPE™ when administered as a Single-dose Subretinal Injection in Subjects with Geographic Atrophy (GA) Secondary to Dry Age-related Macular Degeneration (d-AMD).

To evaluate the safety and potential efficacy of Eyecyte-RPE™ in subjects with GA secondary to d-AMD.

Open to recruitment
Clinical Trial

A Phase-3, Double-Masked, Two-Arm, Multiple-Dose, Parallel Group, Randomized, Multicenter, Active-Controlled, Comparative Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of Aflibercept Intravitreal Injection and Eylea (Aflibercept) Intravitreal Injection in Patients with Diabetic Macular Oedema (DME).

A study to compare the efficacy, safety, and immunogenicity of aflibercept intravitreal injection and Eylea (Aflibercept) intravitreal injection in patients with Diabetic Macular Oedema (DME)

Completed
Clinical Trial

A Phase 2/3, Randomized, Double-Masked, Parallel Group, Multicentre, Comparative Clinical Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Immunogenicity of Intas Bevacizumab and Ranibizumab Intravitreal Injection in Participants with Neovascular (wet) Age Related Macular Degeneration

Comparative Clinical Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Immunogenicity of Intas Bevacizumab and Ranibizumab Intravitreal Injection in Participants with Neovascular (wet) Age-Related Macular Degeneration

Closed to Recruitment of Participants
Observational Study

Genotype–Phenotype Correlation And Mutation Spectrum in A Large Cohort of Patients With Retinitis Pigmentosa Revealed By Next-Generation Sequencing

Advancing Understanding of Inherited Retinal Diseases

Open to recruitment
Ethics & Participant Protection

Research With Responsibility

Protecting the rights, safety, privacy and dignity of research participants is fundamental to our research programme.

Ethics Committee Oversight

Research involving human participants is subject to appropriate ethical review and oversight before the research begins, wherever applicable.

  • Ethical review of research protocols
  • Review of participant information and consent processes
  • Monitoring of participant safety
  • Protection of participant confidentiality

Participants' Rights

Participation in research is voluntary. Participants are provided relevant information regarding the research and may ask questions before making a decision about participation.

  • Voluntary participation
  • Informed consent
  • Privacy and confidentiality
  • Appropriate communication of research information
Ethics Committee

Ethics Committee Approvals

Certificates and documentation relating to the ethical oversight of research activities at Shri Ganapati Netralaya.

Ethics Committee Approval Certificate 1

Ethics Committee Approval Certificate

Certificate of approval for research activities.

Ethics Committee Approval Certificate 2

Ethics Committee Approval Certificate

Additional ethics and research approval documentation.

Featured Research Interest

Genetic Research in Retinitis Pigmentosa

Understanding inherited retinal disorders can help improve diagnosis, counselling and future opportunities for targeted therapies.

Understanding Retinitis Pigmentosa

Retinitis pigmentosa (RP) represents a group of inherited retinal disorders that can lead to progressive visual impairment. Genetic factors play an important role in many forms of the disease.

Research in inherited retinal disease can help improve understanding of disease mechanisms and support appropriate diagnostic and genetic counselling pathways.

Common Clinical Features

  • Difficulty seeing in low-light conditions
  • Progressive peripheral visual field loss
  • Difficulty adapting between bright and dark environments
  • Progressive changes in retinal function
  • Variable severity and progression depending on the underlying condition

Genetic Testing

Genetic testing may help identify disease- associated genetic variants in selected patients with inherited retinal disorders. Appropriate testing should be considered in the context of clinical evaluation and genetic counselling.

  • Clinical assessment
  • Detailed family history
  • Appropriate genetic testing
  • Genetic counselling

Future Treatment Research

Advances in molecular genetics and retinal science are contributing to research into new approaches for inherited retinal diseases.

These areas include gene-based approaches, molecular therapies, retinal imaging and other emerging strategies. Research findings and treatment availability can change over time.

Research Team

A Multidisciplinary Approach

Research is supported by collaboration between clinical specialists, research professionals and supporting teams.

Ophthalmologists

Clinical expertise and disease-specific research leadership.

Research Coordinators

Study coordination, documentation, participant follow-up and data collection.

Data & Statistics

Structured data management and research analysis support.

Collaborators

Academic, clinical and scientific collaborations supporting research.

Research Interests

Areas of Scientific Interest

Current and potential areas for clinical and translational research.

Cataract and refractive surgery
Retina and vitreoretinal disease
Corneal disorders
Glaucoma
Pediatric ophthalmology
Oculoplasty
Inherited retinal disorders
Ophthalmic imaging
Surgical outcomes

Collaboration Opportunities

We welcome opportunities to collaborate with academic institutions, hospitals, clinicians, researchers and scientific organisations on meaningful ophthalmic research.

Discuss a Research Collaboration
Why Research at SGN

Connecting Research With Real-World Eye Care

Our research approach is closely connected to everyday clinical practice and the needs of patients.

Clinical Environment

Research questions are informed by real-world clinical challenges and ophthalmic patient care.

Outcome Focused

Research aims to generate evidence that can contribute to measurable improvements in diagnosis and treatment.

Patient Centred

Participant welfare, communication and informed decision-making remain central to responsible research.

Innovation

We remain interested in new diagnostic, therapeutic and technological approaches that may improve eye care.

Get Involved

Connect With Our Research Team

For research collaboration, study-related enquiries or information regarding research opportunities, please contact the hospital's research team.

Research Centre

Shri Ganapati Netralaya
Eye Hospital & Research Centre

Research Enquiries

Please contact the hospital through the official communication channels for research-related enquiries.

Collaboration

Academic and institutional research collaboration enquiries are welcome.

Research information: Research studies, eligibility criteria, recruitment status and research procedures may change over time. Participation in a research study is subject to the applicable study protocol, eligibility criteria, informed consent and appropriate ethical oversight.